Goat Secondary Antibodies
Cayman Chemical (+)-Naproxen (sodium salt), Purity: ≥95%, CAS: 26159-34-2, 10 g
An NSAID and COX inhibitor; inhibits COX-1 and COX-2 in COS-1 cells expressing the human enzymes (IC50s = 4.8 and 28.4 µM, respectively); inhibits TXB2 and PGE2 production ex vivo in isolated rat blood (IC50s = 5 and 13 µM, respectively)
Cayman Chemical Perfluoroheptanoic Acid, Purity: ≥90%, CAS: 375-85-9, 50 g
A perfluoroalkyl substance; prenatal exposure is positively correlated with preterm birth, primarily in male infants; positively correlated with fat mass, BMI, and waist circumference in females but negatively associated with BMI, waist circumference, and weight-to-height ratio in males
Cayman Chemical InRleukIn6RaCD126 RabbI 100uL
An agonist of NPY receptor Y5 inhibits forskolin-induced cAMP production in HEK293 cells expressing the Y5 receptor (EC50 17 nM) selectively binds to Y5 (IC50 0.24 nM in HEK293 cells expressing the human receptor) over Y1 Y2 and Y4 (IC50s 530 500 and 51 nM respectively in BHK-21 cells expressing the human receptors) increases VEGF levels as well as endothelial branch length and branch points in 4T1 cells in a concentration-dependent manner induces relaxation of vasopressin-precontracted rat mesenteric arteries at 1 UM increases food intake in rats at 0.2 and 2 nmol/animal i.c.v.
Cayman Chemical 4-Methylumbelliferone, Purity: ≥98%, CAS: 90-33-5, 500 g
A synthetic coumarin with diverse biological activities; inhibits hyaluronic acid synthesis in PC3-ML and DU145 cells (IC50s = ~0.4 mM for both); inhibits the growth of PC3-ML, DU145, C4-2B, LNCaP, and LAPC-4 prostate cancer cells (IC50s = 0.2-0.4 mM) and invasion and chemotactic motility of PC3-ML and DU145 cells in vitro; reduces tumor growth and microvessel density in a PC3-ML mouse xenograft model at 225 and 450 mg/kg twice per day; active against H. pylori and V. cholerae in vitro (MICs = 59 and 100-200 μg/ml, respectively); ex/em = 320 and 360 nm at low and high pH, respectively/455 and 445 nm at low and high pH, respectively.
Cayman Chemical 1,2-Dioleoyl-3(R)-trimethylammoniumpropane (chloride), Purity: ≥95%, CAS: 328250-28-8, 100 mg
A cationic lipid; lipoplexes containing R-DOTAP and encapsulating siRNA targeting CYP19A1 decrease aromatase activity in MCF-7 cells; vaccination with an HPV 16 protein E7 peptide in R-DOTAP-containing liposomes induces IFN-γ production by CD8+ T cells and TILs and decreases tumor size in a murine cervical cancer model; subcutaneous immunization with recombinant influenza B hemagglutinin using R-DOTAP as an adjuvant increases IL-2 and IFN-γ production in CD4+ T cells isolated from mouse draining lymph nodes and spleen
Seracare Life Sciences Inc ANTI-HU IGG (H+L) F(AB )2 HRP
Affinity purified polyclonal antibody, F(ab)2 fragment, to Human IgG, heavy and light chains (whole IgG). Made in Goat and labeled with horseradish peroxidase. Product is in lyophilized form. Each lot is tested to assure specificity and lot-to-lot consistency using KPL's in-house ELISA assay.
Seracare Life Sciences Inc ANTI-RBIGG(H+L)F(AB )2HSADL488
Affinity purified F(ab')2 fragment polyclonal antibody to Rabbit IgG, both heavy and light chains (whole IgG) made in Goat and labeled with DyLight 488. Product has been cross-adsorbed to human serum to minimize cross-reactivity to human immunoglobulin. Product is in lyophilized form. The conjugate is designed for use in a variety of immunofluorescense assays, including immunohistology, flow cytometry, Western blotting, microarrays and Fluorophore-Linked Immunosorbent Assays (FLISA).
Seracare Life Sciences Inc ANTI-BOVINE IGM (U) AB BIOTIN
Affinity purified polyclonal antibody to Bovine IgM heavy chains (mu) made in Goat and biotinylated. Product is in lyophilized form. Each lot is tested to assure specificity and lot-to-lot consistency using KPL's in-house ELISA assay.
Seracare Life Sciences Inc ANTI-RBIGG(H+L)F(AB )2 FRAGHSA
Affinity purified polyclonal antibody, F(ab)2 fragment, to Rabbit IgG, heavy and light chains (whole IgG). Made in Goat. Product has been cross adsorbed to human serum to minimize cross reactivity to human immunoglobulin. Product is in lyophilized form. Each lot is tested to assure specificity and lot-to-lot consistency using KPL's in-house ELISA assay.
Seracare Life Sciences Inc ANTI-MS G+M (H+L) AB BIOTIN
Affinity purified polyclonal antibody to Mouse IgG and IgM, heavy and light chains (whole IgA, IgG, IgM) made in Goat and biotinylated. Product has been cross-adsorbed to human serum to minimize cross-reactivity to human immunoglobulin. Product is in lyophilized form. Each lot is tested to assure specificity and lot-to-lot consistency using KPL's in-house ELISA assay.
Seracare Life Sciences Inc ANTI-MS IGG(G) F(AB )2 FRAGHSA
Affinity purified polyclonal antibody, F(ab)2 fragment, to Mouse IgG heavy chains (gamma). Made in Goat. Product has been cross adsorbed to human serum to minimize cross reactivity to human immunoglobulin. Product is in lyophilized form. Each lot is tested to assure specificity and lot-to-lot consistency using KPL's in-house ELISA assay.
Cayman Chemical Penfluridol, Purity: ≥98%, CAS: 26864-56-2, 500 mg
A typical antipsychotic; binds to dopamine receptors (IC50 = 5.6 nM); binds to dopamine D4 and 5-HT receptors (Kis = 31 and 63.1 nM, respectively); inhibits stereotypic behavior induced by apomorphine in cynomolgus monkeys at 1.25 and 2.5 mg/kg; inhibits proliferation of TNBCs (IC50s = 6-8 µM); inhibits migration and invasion of TNBCs and decreases the expression of integrin α6 and β4; reduces tumor growth and metastasis in a 4T1 orthotopic mouse model at 10 mg/kg per day
Seracare Life Sciences Inc ANTI-MS IGG(H+L) AB HSA BIOTIN
Affinity purified polyclonal antibody to Mouse IgG, heavy and light chains (whole IgG) made in Goat and biotinylated. Product has been cross-adsorbed to human serum to minimize cross-reactivity to human immunoglobulin. Product is in lyophilized form. Each lot is tested to assure specificity and lot-to-lot consistency using KPL's in-house ELISA assay.
Cayman Chemical 4-Methylumbelliferyl Caprylate, Purity: ≥98%, CAS: 20671-66-3, 10 g
A fluorogenic substrate for C8 esterase; is cleaved by C8 esterase to release the fluorescent moiety 4-MU; ex = 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively; em = 445 to 455 nm, increasing as pH decreases